It is a typical week of the week. Before the hustle and bustle of the day begins, drink your collagen coffee while scrolling your social feeds. In succession, almost every blow is a post about the next best anti-aging elixir, the connection, movement or food. Then NAD dipped a supplement, which is advertised by people like Hailey Bieber and Kendall Jenner as anti-aging gold mine that deserves to use for a lifetime. But is it really?
NAD – Short for Nicotinamide -aden -Dinucleotide – is a cellular coenzyme that is responsible for transforming food into usable energy. It also plays an important role in the DNA repair, in cellular processes and the function of the immune system. Although the body naturally produces NAD, its production of NAD decreases with increasing age.
The older you get, the more difficult it is for your body to keep you healthy and to process nutrients into energy. That is why they feel sluggish and their risk of illness or injuries increases. For this reason, people were interested in NAD supplementation.
The idea is that the addition with NAD could equate more energy, better health and maybe even a longer, healthier life. Before you send to the Send the button in your virtual shopping cart, however, let us open what happens to your body when you take NAD nutritional supplements.
Nad understand
NAD acts as a coenzyme in the body to support several metabolic processes. Essentially, coenzyme support other molecules in every work for which they are designed. You would not work without this metabolic path.
Then there are DNA that are easily damaged by life stressors, UV radiation as well as alkylating and oxidative molecules. Fortunately, your body is pretty good at maintaining the DNA integrity by sending NAD to do the work. Without getting into the complex nature of the DNA repair paths, NAD calls in molecules to quickly nourish and rejuvenate the damaged DNA cells.
As already mentioned, NAD acts as an assistant or middle man, which makes things happen and the communication between the cells in the entire body. Without enough NAD, simple processes in the body can take longer, partly due to poor communication. This could look like an endangered immune system (also known as it is often ill), poor stress response and an increased risk of obesity, type -2 -diabetes, metabolic syndrome, cancer and other degenerative diseases.
Possible effects of the NAD supplementation
With the inevitable decline of the NAD at the age of NAD, their energy generation and cell repair also decrease. This reduction leads to loss of energy, mental fatigue, wrinkles and frequent illness. Although there is no way to prevent this, you can fill the gaps with NAD supplementation.
Increased cellular energy
If you eat food, it is broken down into molecules to produce energy in the form of ATP. During this process, NAD acts as an enzyme that makes it easier to convert NADH to ATP. Without enough NAD, the body has a difficult time to produce ATP in good time, which can lead to you feel sluggish and tired. The addition with NAD could increase the production of cells by increasing the ATP levels, which improves the metabolism and reduces the tiredness.
Studies on people with chronic fatigue syndrome evaluated the safety and effectiveness of the NAD supplementation in terms of tiredness, quality of life and sleep quality. The general consensus is that the addition with NAD has a positive impact on the quality of life and that health parameters such as fear, energy and reaction of the immune system improve.
Improved cellular repair
Since NAD is involved in mechanisms of the DNA repair, which help to damage cells from damage caused by stress, oxidative damage and aging, higher mirrors (due to supplementation) can promote a more efficient process.
For example, a study examined the role of NAD supplementation in DNA repair. The researchers found that supplementation reduced the accumulation of endogenous DNA damage and improved DNA repair capacity. Ultimately, the addition with NAD can positively influence the DNA repair in connection with aging and neurodegenerative diseases such as Alzheimer’s disease.
Improved cellular communication
Cellular communication is of essential importance for general health, well -being and longevity. If cells cannot access messages immediately, aging will progress.
Since NAD looks like an assistant, it is his job to ensure that things happen quickly and efficiently. Restoring NAD to young people means that their body’s things quickly check the daily task list from the daily task list. It restores the cell signal function and reduces stress.
Possible negative side effects
If all of this sounds too good to be true, this can be because some studies report mild side effects of using NAD nutritional supplements, especially in high doses. Over 500 milligrams of nicotinamide is not recommended. Studies show that excess supplementation increases the risk of vascular diseases, neurodegenerative diseases and chronic kidney diseases. Other symptoms, including diarrhea, slight bruises and increased wound bleeding, can be observed. Over 3000 milligrams can cause nausea, vomiting and liver damage.
It is important to consult a health service provider before taking NAD, especially if you have an existing illness or take medication.
Current research
Although it is available, it is not complete or conclusive to a NAD supplementation in humans. There is always space for ongoing studies and results.
However, the use of a NAD supplement for diseases such as age-related cognitive decline, neurodegenerative diseases (Alzheimer’s, Parkinson’s) and cardiovascular health have some promising advantages. So far, research has shown the following.
- Age -related cognitive decline: Research on the use of NAD nutritional supplements for cognitive decline is promising. However, most of the results were in animal studies. Nevertheless, a recent overview showed that NAD supplementation can preserve cognitive health in the event of a variety of age-related diseases, including Alzheimer’s disease and dementia.
- Neurodegenerative diseases: Healthy brain alternating is particularly important when preventing neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Huntington diseases. The NAD mirrors decrease during the normal aging of the brain. Over time, this leads to cellular damage, inadmissible disposal of cell waste, an impairment of the stress reaction, the delay of the DNA repair, the exhaustion of stem cells and inflammation. The addition with NAD can return NAD to healthy values and prevent further damage to brain cells. Although promising, more research in humans are required.
- Heart cycle health: Cardiovascular diseases often contain metabolic disorders (abnormal lipid and glucose metabolism), oxidative stress (cell damage) and inflammation (poor cell signaling). These stress markers make it difficult for the heart to function properly and contribute to cardiovascular diseases. Even in the heart, the NAD Homöostasis is important. An overview showed that the increase in the NAD nutritional supplements has favorable effects on heart health and has a profound influence on the heart cycle.
Dosing and delivery methods
The two most common delivery methods for NAD are oral tablets and IV injections. NAD tablets are available online, normally as a NAD predecessor -nicTinamide -Riboside (nr) and/or niacin (NADH). These precursor preparations influence the positive NAD mirror strongly.
NAD+ IV injections are available in local clinics and are generally not covered by insurance companies. These intravenous injections use a more direct source of NAD. However, it must be dripped over the course of at least two hours to prevent unwanted events such as a quick heartbeat, nausea and fear.
The best dosage and delivery method from NAD is still being examined. However, most reported side effects only occur in doses that are used higher than the clinically used or for the supplementation used for daily supplementation. Therefore, take the dosage recommended by a health service provider and avoid this to exceed this to prevent side effects and potential health risks.
Natural ways to increase NAD
If you are not ready to make the NAD supplement -there are ways to naturally increase NAD with simple changes to the lifestyle. You need to know the following.
- Exercise: Regular aerobics and strength training training has a regenerative influence on the NAD values and can even bring them back to young adults. A study from 2019 showed that aerobic and resistance training Nampt, the forerunner of NAD, increases.
- Circadian rhythm & sleep: Your circadian rhythm (also known as 24-hour clock) and sleep pattern correlate directly with the NAD+ production. Enough sleep is the key to maintaining appropriate levels – sleeping deprivation and disturbed sleep patterns are associated with a reduced NAD+ synthesis.
- Environmental stress (heat/cold): Cold -Tungs pools and saunas can help increase NAD. Exposure compared to extreme hot and cold temperatures can particularly strain the body and trigger the production of NAD+.
- Certain foods: A balanced diet can deliver all the required NAD, especially if you include food that is rich in vitamin B3 (niacin) and leaf green vegetables. Vitamin B3 (also known as niacin) can easily be found in meat, fish, dairy products, avocado and whole grains and is the forerunner of NAD. Niacin converts for use in cell metabolism in NAD. Tryptophan, a forerunner for NAD, can be found in turkey, chicken, fish, nuts and soy. Leaf green vegetables, including broccoli, colored cabbage and green onions, also contain connections that positively influence the NAD values.
Conclusion
While NAD is promising as an anti-aging power house, there are still many unknown people in relation to NAD supplementation. Before making changes to your health routine and supplement, speak to a health service provider like a registered nutritionist to make sure you make the right choice for you. In the meantime, it is the cornerstone for the promotion of cell health and general well -being if you lead your body free of tobacco and other stressors with nutritious foods and a healthy lifestyle.